-- Jordan Raanan. Neal has played well in the past while filling in for Jamal Adams and appears to be in line to get another opportunity, having replaced Jones in the fourth quarter of Seattle's win over Detroit. Betting nugget: Detroit has covered six straight road games, but it is 0-10-1 outright in its past 11 road games (0-9-1 under Dan Campbell). This could be Rodgers' breakout game. Another one of its Week 5 NFL predictions: The Packers (-3) cover on the road against the Bengals in a matchup of 3-1 teams. Arizona has given up 17 sacks while the Eagles have 10 on the season, but Palmer called the Eagles' front seven one of the best he will face this year. Week 5 NFL predictions: Scores for every game - ESPN FPI prediction: HOU, 64.0% (by an average of 5.0 points), Matchup must-reads: How Watson's 'NFL experience' began as ball boy for the Falcons TE Hooper could be the next Falcon to cash in Quinn not worried about job, his staff, 1 p.m. Yes, he's 2-0, but the Saints will need more from Bridgewater, 1 p.m. When the draft ended, there was a total of 43 trades, breaking . -- Turron Davenport. Washington opened the. Baby's pick: Cardinals 24, Bengals 21 That includes losses to the Titans and Colts in the past two weeks. The Bears, however, are the league's least-equipped team to exploit that shortcoming. We answered the biggest post-draft question for all 32, LB Barrett's 2-year-old daughter drowns in pool, Deion 'ashamed' after only 1 HBCU player drafted, Sources: NFL eyes May 11 to release schedule, Teams set NFL record with 43 trades during draft, Jets coach Saleh: Rodgers making 'presence felt', Cowboys scout emotional as team drafts his son, Rams use 'Mr. The model also enters Week 5 of the 2021 season on an incredible 124-82 run on top-rated NFL picks that dates . What to know for fantasy: With two games of seven-plus targets already this season, plus a TD reception in Week 4, Bengals tight end Hayden Hurst has potential. The answer is to be determined, Cruz expects Minshew will lead Jags over Allen's Panthers (1:17), Week 5 NFL game picks, schedule guide, fantasy football tips and more, Which NFL teams still have roster holes? Jets' high-priced, underperforming offensive line receives wake-up call Eagles RBs coach Duce Staley: 'A lot of Jordan and a lot of Miles', 1 p.m. Read more. ET | CBS The story of the Cowboys scout and prospect son Dallas just drafted, Legacy pick: Cardinals take great-great-nephew of team's first-ever draft pick, Buccaneers coach Todd Bowles explains handling of TE Cameron Brate's concussion, Veteran WR Cole Beasley retires after 11 NFL seasons, QB Kenny Pickett, Steelers begin work to get on 'same page', The Steelers' 2022 quarterback journey, and what happens next, LB Jamie Collins joins Patriots for fourth time, Swift likely out again vs. Patriots, source says, Bears designate WR N'Keal Harry for return; OL Cody Whitehair headed to IR, Inside Kelly Kleine's historic journey, from Vikings to Broncos, Justin Fields, Bears' struggling passing game looking for answers, Vikings riding ups and downs as Cousins learns new scheme, Dolphins' Mike McDaniel not fretting criticism over Tua Tagovailoa, Inside Jets' trade pursuit of Tyreek Hill, and how they rebounded, Dolphins say QB Tua Tagovailoa ruled out for Week 5 game vs. New York Jets, Browns' schedule gets difficult from now on, Garrett back at Browns practice for first time since car crash, Everything you need to know for the draft, The Seahawks have needed every bit of Geno Smith's unlikely success, Andy Dalton gave Saints' offense a spark, but bigger issues loom after 1-3 start, Saints' Alvin Kamara (rib) expects to play against Seahawks, Titans rookie WR Treylon Burks exits game with leg injury, Rivera OK with 'frustrations' amid 1-3 start, Commanders patient with Wentz despite rough stretch, RB Robinson returns to practice after being shot in robbery attempt, After loss, the Jaguars look to rebound against AFC South, How LSU and the SEC prepared Texans rookie Derek Stingley Jr. for the NFL, Former Jaguars QB Blake Bortles says he 'quietly' retired, Jimmie Ward year away from being among rarefied 49ers company, Mayfield struggles, but Panthers don't have another option, Nick Bosa says 49ers' defense has personnel to be 'best in the league', Mayfield takes blame for offense's struggles amid 1-3 start, Darnold's return from IR not close, coach Matt Rhule says, Miles Sanders' emergence makes the Eagles so much better, Defense keeps Cardinals afloat while offense figures it out, Jerry Jones: An 'injustice' not to give coach McCarthy credit. Additionally, ESPN Stats & Information research provides a stat to know for each game, and the Football Power Index (FPI) goes inside the numbers with a matchup rating (on a scale of 1 to 100) and a game projection. The Saints, meanwhile, have committed an NFL-high 11 turnovers -- including five interceptions in three games from Jameis Winston -- so the opportunity will be there. Read more. Steelers 27, Jaguars 20 -- Jeremy Fowler, The Seahawks are coming off one of the more dominant halves of football they've played under Pete Carroll, outscoring the Colts 36-3 and holding them to 32 yards in the second half last week. -- Eric Woodyard. Jets 20, Browns 17 -- Rich Cimini, Old friend Josh McCown is healthy and completing 70 percent of his passes, and the Jets have won two in a row with the kind of run-pass balance that the Browns should study. Read more. The Vikings are banged up on offense but probably still good enough to squeak out a close victory. This should be a prime spot for them to get on track, even with the uncertainty surrounding receiver Stefon Diggs. They also rank No. 125 attempts). (Game times are Sunday unless otherwise noted. -- Courtney Cronin. -- Mike DiRocco. Stat to know: JuJu Smith-Schuster's 15 receiving yards against the Bengals were the fewest he has had in a regular-season game in which he registered at least one reception. Here are some lines that could change after this week's slate concludes. Lions 28, Panthers 20 -- Michael Rothstein, This is the second of three consecutive road games for the Niners, and they're coming off a trio of games they lost by a combined eight points. And the Chargers have allowed 5.4 yards per rush, the second worst in the NFL. The Bills' offense -- which has gone three-and-out on 48 percent of drives this season, second most in the NFL -- will be playing short-handed at wide receiver because of a thumb injury to No. 2023 NFL Draft props, picks: Michael Mayer Under 23.5 Cowboys' running game will be tested on Sunday (1:06) Herm Edwards and Tedy Bruschi discuss the outcome of what could be a high-scoring game in Dallas. Lions (1-3) at Patriots (1-3) 1 p.m. NFL Week 5 picks, predictions: Who wins each Week 5 NFL game? Last year alone, Mahomes threw seven touchdowns with no interceptions in two games as the Chiefs scored a combined 89 points. The 49ers are tied for second in the NFL in sacks with 15 -- which is not a good omen for Mayfield. Betting nugget: All four Bills games have gone under the total this season. Even without D'Andre Swift, the Lions' ground attack is rolling, and that won't stop against New England. Also note that the Redskins enter the game ranked 29th in rushing yards allowed per game (147.5). -- John Keim, Bold prediction: Titans quarterback Ryan Tannehill will finish with 300 passing yards in a win over the Commanders. Top Week 5 NFL predictions One of the model's strongest Week 5 NFL picks is that the Titans (-2.5) cover against the Commanders in almost 60% of simulations. 1 overall pick, are hours away from being on the clock -- which means the 2023 NFL draft has arrived. On the flip side, the Packers might have to run the ball with Aaron Jones given the turf toe injury to Davante Adams, who caught two touchdown passes in the previous meeting in Dallas. -- Mike Triplett, Everything you need this week: "His quickness with power is awesome," said Rivers about Miller, who has 16 career sacks against the Chargers. CFB: Year in review: Best games of 2020 play. The NFL Week 5 schedule features a bevy of intriguing matchups including the Rams vs. Seahawks on Thursday Night Football in a matchup between two NFC East teams with championship aspirations; the Browns vs. Chargers in a battle between two surprising contenders in the AFC; the 49ers vs. Cardinals in a critical NFC West tilt featuring MVP See Week 5 rankings. -- Vaughn McClure. What to know for fantasy: Through four weeks, there were 44 players with at least 25 carries. It's all here to help get you ready for a loaded weekend of NFL football. Moody's pick: Eagles 30, Cardinals 17 Everything you want to know is here in one spot to help you get ready for a loaded weekend of NFL football. Read more. Matchup rating: 52.4 | Spread: NE -15 (42), What to watch for: Can the Redskins do anything to slow the Patriots' offense? Raiders 23, Ravens 16 -- Paul Gutierrez, Three key players from the Packers playoff victory over the Cowboys are gone -- Jared Cook (the tight end who caught the sideline pass to set up the game-winning field goal), Micah Hyde (the safety who had an interception) and T.J. Lang (the Pro Bowl guard who protected Aaron Rodgers). I've been talking with execs, scouts, coaches and other evaluators around the league to get the latest surrounding how each team might use their 2023 NFL draft . Betting nugget: The Broncos are 1-7 ATS in their past eight games. Gutierrez's pick: Bears 20, Raiders 16 -- Katherine Terrell, Bold prediction: Ryan Neal will take over for Josh Jones in the starting lineup and spark Seattle's struggling defense with a game-changing takeaway. Read more. Facebook; Twitter; Facebook Messenger; Pinterest; Email; Scoring is up across the NFL. NFL draft 2023 betting cheat sheet: tips, picks, plays to make -- Sarah Barshop, Bold prediction: The Falcons, who have been outscored 38-10 in first quarters this season, will actually have the lead after the first frame in Houston. The Cardinals have allowed a league-high 20 sacks; the Bengals are right behind them at 19. Walder's pick: 49ers 23, Panthers 14 The Bengals as a whole have an NFL-worst 2.8 yards per rush and NFL-low 1.5 yards before first contact. Chicago knows how dangerous Minnesota's run game can be, so they'll stack the box to try to take away Dalvin Cook and make Cousins beat them with his arm. Betting nugget: Mahomes is 7-1 outright and 6-2 ATS against Las Vegas. What to know for fantasy: Baker Mayfield averaged one touchdown pass every 18 attempts as a rookie. -- Sarah Barshop, Bold prediction: CeeDee Lamb will finish with more catches than Cooper Kupp. Cronin's pick: Giants 21, Vikings 17 ET | Fox Read more. What to know for fantasy: Curtis Samuel's target share is nearly twice that of DJ Moore (24.1% to 12.1%) with Kyle Allen under center for the Panthers this season. With a banged-up Steelers defense that has struggled since T.J. Watt's Week 1 injury, this game has the potential for any number of Buffalo offensive superlatives. What to know for fantasy: Murray leads the NFL with 187 opportunities this season (pass-plus-rush attempts). FPI prediction: ARI, 56.4% (by an average of 1.8 points), Matchup must-reads: Miles Sanders' emergence makes the Eagles so much better Defense keeps Cardinals afloat while offense figures it out, What to watch for: Matthew Stafford has been sacked 16 times this season, which is tied for the second most in the NFL. Through the first four games, the Giants have played three starting offensive line combinations up front. Raanan's pick: Vikings 27, Giants 13 Gregg Rosenthal went 10-6 . And for fantasy managers looking to make all the right moves, Graziano and Fowler name must-start sleepers and point out potential fantasy flops of the week. Commanders patient with Wentz despite rough stretch RB Robinson returns to practice after being shot in robbery attempt, What to watch for: Texans running back Dameon Pierce is coming off the first 100-yard game of his career (which included a 75-yard TD run) and ranks 10th in the NFL in rushing. That should change against a Tampa Bay team that is averaging 31 points per game and allowing 29. NFL Week 5 Early Odds, Picks & Predictions (2022) | BettingPros CFB: The way-too-early top 25 for 2021 New England's slide has coincided with losing DT Lawrence Guy (shoulder), who might be ready to return. NFL Expert Picks, Predictions, Lines: Week 5 - College Football News Big Ben's 3-1 home-away touchdown ratio since 2015 looms large here, especially with Bell looking like his 2016 self and Jacksonville entering the week allowing 5.7 yards per carry, the league's worst by a large margin. -- Mike Reiss. Their offense is clicking on all cylinders, and their defense finally showed signs of life in the second half Sunday, holding Dallas to a mere six points. Betting nugget: Minnesota is 22-10-1 ATS after a loss under Mike Zimmer. Stat to know: The Chiefs have won six straight home games on Monday Night Football with the last loss coming in 2004 against the Patriots. ET | Fox However, Miami is vastly improved in that area, allowing just 3.1 yards per rush and 78 yards per game this season. Read more. The Bills aren't known for a traditional ground game, but the Steelers' defense is giving up an average of 131.5 rushing yards per game. Full schedule | Standings That stat line would be worth 259.6 points, not much different from the 260.1 points that Allen produced last season. -- Marcel Louis-Jacques. Walder's pick: Seahawks 19, Saints 16 What to know for fantasy: Pierce has more than 100 scrimmage yards and a rushing score in consecutive games. However, Arizona's primary hope for winning this game lies with its run defense. 2022 NFL Expert Picks | ESPN Cowboys D reaching elite levels of legendary Doomsday Defense? But Trubisky is making his first career start on Monday Night Football. They haven't lost three straight road games since 2018. -- Paul Gutierrez. Stat to know: The Niners' Jeff Wilson Jr. has scored multiple rushing touchdowns in two straight games. Bengals 13, Bills 9 -- Mike Rodak, The Bengals have a tough matchup against one of the league's best defenses (Buffalo is 10th overall), but it looks like their offense finally has begun to click in the past two weeks. Vikings 27, Bears 26 -- Jeff Dickerson, Cowboys' running game will be tested on Sunday (1:06), Week 5 NFL predictions: Scores for every game, Dolphins' Jaelan Phillips, teammates inspired by mentoring incarcerated teens, What adding Odell Beckham Jr. would mean for the New York Jets, Extending Vikings star Justin Jefferson: what it could cost, possible sticking points. The Chiefs, averaging 33.8 points per game, have scored more than 30 points with quarterback Patrick Mahomes as the starter 13 times in his 20 career starts. See Week 5 rankings. Stat to know: Rodgers is averaging 6.2 air yards per attempt, his fewest through four games since becoming a starter in 2008. NFL Nation reporters give their picks for Week 5, including whether the Cowboys can bounce back against Aaron Rodgers and the Packers. 3 all-time rusher Barry Sanders, 1 p.m. Louis-Jacques' pick: Bills 14, Titans 10 Our NFL Nation reporters bring us the keys to every game, a bold prediction for each matchup and final score predictions. Most important, Rodgers is 13-2 in those games, dating back to 2008. NFL picks against the spread for Week 5. This week's draft seemingly begins with the second overall pick -- excluding Tuesday's wild odds move for the top pick -- but it could take a few wild turns right after that. Betting nugget: Over the past 15 seasons, teams favored by at least seven points in international games are 7-0 ATS (6-0 ATS in London). Week 5 brings some more great matchups and potential upsets. NFL Power Rankings Week 5 bet now, bet later Week 5 spot bets Under 50.5 (-110) Combined, both teams have begun the season 3-5 O/U while the Bengals are riding a three-game Under. -- Rich Cimini. Herm Edwards and Tedy Bruschi discuss the outcome of what could be a high-scoring game in Dallas. ET | FOX Spread: NE -3.0 (45.5). Stat to know: Brady's only three-game losing streak in his career came from Weeks 4 to 8 in 2002, his second season as a starter. Since 2011, games with totals of 55 or higher are 33-22-1 to the over. He has also been sacked 11 times, tied for the eighth most in the NFL. Matchup rating: 42.0 | Spread: PHI -14.5 (43.5), What to watch for: The Eagles are paper-thin at cornerback after injuries to Ronald Darby and Avonte Maddox. As Giants defensive coordinator Wink Martindale said of the Packers QB, 'It's like owning a python and saying, 'Don't worry about it, he won't bite.'" What to know for fantasy: Pittsburgh's Diontae Johnson owns a 20.5% target share this season from Rudolph, up from his 9.7% rate with Ben Roethlisberger under center. Matchup rating: 50.5 | Spread: BAL -3.5 (44), What to watch for: The Ravens' defense has a penchant for giving up big plays. FPI prediction: NO, 72.6% (by an average of 6.9 points), Matchup must-reads: The Seahawks have needed every bit of Geno Smith's unlikely success Andy Dalton gave Saints' offense a spark, but bigger issues loom after 1-3 start Saints' Alvin Kamara (rib) expects to play against Seahawks, What to watch for: Washington has done a nice job stopping the run the past two weeks against the Eagles and Cowboys, allowing an NFL-best 2.27 yards per carry and tying for second at 67 yards allowed during that stretch. HOU-JAX | SF-CAR | PHI-ARI That would help against a Lions offensive line featuring three solid first-round picks in left tackle Taylor Decker (2016), center Frank Ragnow (2018) and right tackle Penei Sewell (2021). Jets 24, Browns 10 -- Pat McManamon, The Lions are strong against the run, which makes the timing of Panthers quarterback Cam Newton finding his timing against New England most important. For context, 5.2 yards per rush with McCoy on the field would rank fifth in the NFL among all teams this season, as opposed to 27th when McCoy isn't on the field. Theyll give up some yards and some plays. With DT Fletcher Cox still working through a calf injury, there's a chance Palmer will have a little more time to operate. Irrelevant' pick on Toledo's Johnson, Chargers go all-in on TCU with Duggan pick in 7th, 10 fantasy football breakout players for 2023, Will Levis opens up about emotional draft day, Steelers' first draft under Omar Khan was 'aggressive' and achieved high marks, After hoopla of going No. See Week 5 rankings. -- Ben Baby. NFL: Mahomes favorite for game's MVP Matchup rating: 63.6 | Spread: HOU -5 (49), What to watch for: Will wide receiver DeAndre Hopkins top 100 receiving yards against Atlanta? Get the latest NFL Week 5 picks from CBS Sports. Betting nugget: Since the start of the 2016 season, Arizona is 3-13 ATS in 1 p.m. Stat to know: Chargers receiver Keenan Allen leads the NFL with 452 receiving yards, and he is the only player with more than 400. The 2023 NFL draft wrapped up Saturday and through five rounds, 12 quarterbacks were selected -- the most in the common draft era. The 2023 NFL Draft continues today in Kansas City! 2023 NFL Draft Index - University of Texas Athletics Betting nugget: This is the 63rd straight regular-season game that Brady will be favored in, breaking a tie with Steve Young (1993-97) for the longest streak by a quarterback in the Super Bowl era. Las Vegas Raiders vs. Kansas City Chiefs picks, predictions NFL Week 5 Stat to know: The Titans rank 28th in the NFL in both sacks allowed (17) and pressure rate (34.0%). There will be 259 total selections over a three-day period . QB Teddy Bridgewater is 2-0 lifetime against the Jets, who look to go over .500 for the first time since a 1-0 start in 2018. For the season on third downs, he's completing only 48.9% of his passes and owns a 78.0 passer rating. Herbert also totaled five touchdowns. Spread: GB -8.0 (41), What to watch for: This could be a nightmare matchup for the Packers' defense. But since 2017, his 29% completion rate ranks 38th out of 43 passers with at least 50 such attempts. 2022 NFL Expert Picks | ESPN FPI prediction: NE, 85.7% (by an average of 14.7 points), Matchup must-reads: Meet Brady's most trusted teammate: His 1995 shoulder pads Redskins' January decision to maintain status quo looks bad in hindsight Patriots' offense searching for identity, as it did in 2018, 1 p.m. NFL picks, predictions for Week 5: Cardinals crush 49ers; Steelers stop