TCTMD is produced by the Cardiovascular Research Foundation (CRF). Dis. Cardiologist came in and looked me over. Evaluating and Caring for Patients with Post-COVID Conditions: Interim Guidance. Although POTS was previously recognized as a condition that can develop after SARS-CoV-2 infection2, data on its potential development after vaccination have been scarce. Si vous ne souhaitez pas que nos partenaires et nousmmes utilisions des cookies et vos donnes personnelles pour ces motifs supplmentaires, cliquez sur Refuser tout. eCollection 2023 Jan. Publishers note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. The Moderna and Pfizer BioNTech vaccines prevented COVID-19 infection in cancer patients, particularly in those whose treatment concluded more than six months before vaccination, say researchers at Stanford, Harvard and the VA. December 2, 2021 - By Krista Conger. However, the odds ratio (1.1) was non-significantly higher, probably due to the low sample size. Interested in more discussions like this? Nat Cardiovasc Res 1, 11191120 (2022). POTS is a common condition affecting an estimated one to three million Americans. As POTS is a frequently under-recognized condition that can cause substantial debility in affected patients4, greater understanding of POTS in general is required to improve overall awareness and rates of appropriate diagnosis and treatment. Tran, V-T., et al. But all of this, he stressed, is pretty speculative.. Get the most important science stories of the day, free in your inbox. Similar findings were observed after repeating the analysis and considering the second vaccination as the index vaccination. Immunol Res. Since early reports of post-acute infection sequelae of SARS-CoV-2 (PASC) emerged in the media,. This content is available for meeting attendees and/or Platinum Members. Provided by the Springer Nature SharedIt content-sharing initiative, Nature Cardiovascular Research (Nat Cardiovasc Res) However, my internet research shows this is also a drug that should be used short term because of the same side effects, permanent muscle twitching, etc.. Provided by the Springer Nature SharedIt content-sharing initiative, Nature Cardiovascular Research (Nat Cardiovasc Res) History of POTS: 610 VAERS Events, 148 to ER, 29 Hospitalized. 286, 434448 (2019). Postural orthostatic tachycardia syndrome (POTS) and other autonomic disorders after COVID-19 infection: a case series of 20 patients Immunol Res. POTS was more likely to be diagnosed than a collection of common primary care diagnoses (OR 1.10; 95% CI 1.03-1.17), although there was a stronger association between vaccination and myocarditis (OR 2.57; 95% CI 1.02-6.77). POTS can follow COVID-19 in previously healthy patients. https://doi.org/10.1038/s44161-022-00177-8 (2022). Early July I started experiencing dizziness, wooziness when I got up to let the dog out. Find more COVID-19 testing locations on Maryland.gov. 2022 Nov 2;14(11):e31006. News-Medical. In the meantime, to ensure continued support, we are displaying the site without styles The vaccine put me directly into a POTs, but perhaps I had POTs previously and it exacerbated my symptoms or I had COVID and did not know it and I developed POTs as others with COVID have experienced. Have now been on Pantoprazole, rabiprazole(sp). What is the relation between COVID-19 vaccination and new POTS-related diagnoses?. When clinically indicated, usually for substantial or persistent symptoms, medication therapy, such as beta-blockers or ivabradine, were prescribed as tolerated for tachycardic response and midodrine for orthostatic intolerance, they add. <3, I have had COVID twice. We therefore cannot exclude the possibility that the incidence of POTS and POTS-associated diagnoses was overestimated. 66, 744754 (2018). Have been put on Linzess, Trulance, and others. Researchers analyzed data on nearly 300,000 patients from the Cedars-Sinai Health System in Los Angeles County from 2020 to 2022 who had either received at least one dose of a Covid vaccine. When comparing patients who developed COVID-19 between two weeks and six months following vaccination, vaccine efficacy appeared to be slightly lower in patients with higher weight and height. 2021;69:205211. Shaw, B. H. et al. However, they found that people diagnosed with COVID-19 are five times more likely to develop POTS after being infected than after getting vaccinated. They said I have a UTI and discharged me with an antibiotic. Given the complex design of our study, which was intended to account for potentially important confounders, the estimated risks are reported in relative terms; that is, after exposure relative to before exposure or POTS-related diagnoses relative to non-POTS-related diagnoses. For more information, visit http://www.crf.org. Jamal, S. M. et al. Prioritizing facilities located in counties with a high Social Vulnerability Index (SVI) ranking to help increase health equity in COVID-19 vaccination is recommended. A number of physicians and patient groups subsequently reached out to us with their experiences and observations, which included increased patient presentations with POTS-like symptoms after COVID-19 vaccination. Federal government websites often end in .gov or .mil. No help with heart rate and GI. For COVID-19-vaccinated individuals, POTS odds were higher 90 days post-vaccination compared to those 90 days prior to vaccination. 2022. Subsequently, they compared the risks of novel POTS diagnosis after COVID-19 vaccination in comparison to novel POTS diagnoses post-SARS-CoV-2 infections. 286, 438448 (2019). 40, 8190 (2017). To obtain Front Immunol. CAS Clipboard, Search History, and several other advanced features are temporarily unavailable. examined the frequency of new POTS-associated diagnoses POTS, dysautonomia, fatigue, mast cell disorders and EhlersDanlos syndrome before and after COVID-19-vaccination12. New-onset POTS can also follow vaccination (Fig. It hurts too bad to eat/drink. Receive the the latest news, research, and presentations from major meetings right to your inbox. The Mayo clinic said they cant see me. Studies have reported POTS as a potential post-acute coronavirus disease 2019 sequela (PASC). mesurer votre utilisation de nos sites et applications. For the vaccine part of the study, the investigators examined electronic medical records from 284,592 vaccinated individuals (mean age 52 years; 57% women). b, Post-infection odds by diagnosis in all patients. https://www.news-medical.net/news/20221214/What-is-the-relation-between-COVID-19-vaccination-and-new-POTS-related-diagnoses.aspx. Heart Rhythm 12, e41e63 (2015). These scenarios include patients who begin having POTS symptoms during the acute phase of COVID-19, and patients who don't present with POTS symptoms until weeks after the acute phase. BMC Med. BMJ Medicine . Med. I was very sick for about 4 months. Toshniwal Paharia, Pooja Toshniwal Paharia. Recognized as a clinical syndrome that manifests with orthostatic intolerance and postural tachycardia, POTS is diagnosed based on clinical features, such as orthostatic dizziness, palpitations and presyncope, and a 10-minute stand test or a tilt table test that demonstrate a heart rate elevation of at least 30 beats per minute from supine to standing position, the authors explain, noting that it has emerged as one of the features of postacute COVID-19 syndromes. New POTS diagnoses within 90days of exposure were identified based on the international classification of diseases (ICD)-9,10 codes or phecode grouping and expressed as a rate per 100,000 exposures. POTS is a clinical syndrome that manifests with orthostatic intolerance and postural tachycardia1. Still, their age was marginally higher (average age of 60 years, 47% were women, and 59% were Whites). Blitshteyn, S. & Whitelaw, S. Immunol. Posted in: Medical Science News | Medical Research News, Tags: B Cell, Cell, Coronavirus, Coronavirus Disease COVID-19, covid-19, Diabetes, Fatigue, Glycoprotein, Heart, Heart Rate, International Classification of Diseases, Mast Cell, Myocarditis, Primary Care, Research, Respiratory, Ribonucleic Acid, SARS, SARS-CoV-2, Severe Acute Respiratory, Severe Acute Respiratory Syndrome, Syndrome, Vaccine. This paper describes the patient experience of POTS, with 75% of participants reporting misdiagnosis and a median diagnostic delay of 2 years. Who can help?? As we continue to navigate and mitigate the SARS-CoV-2 pandemic and long-term post-COVID-19 complications with the help of COVID-19 vaccines, the need to invest in POTS research to advance our understanding, diagnosis and management of POTS a common sequela of both SARS-CoV-2 infection and COVID-19 vaccination has never been more pressing. Maharaj N, Swarath S, Seecheran R, Seecheran V, Panday A, Seecheran N. Cureus. J. Intern. One of the remaining approvals was for severe allergic shock and one was for a type of skin swelling called angioedema. The current proposed pathology for POTS is an inability to regulate blood volume. After vaccination, the odds of a POTS-related diagnosis were 10% higher than the odds of a diagnosis not related to POTS. FOIA Long COVID has a wide range of symptoms, most of which overlap with symptoms of chronic fatigue and POTS: Breathlessness; Brain fog Careers. POTS has been around forever and gets exacerbated by viral illness or in . 69, 205211 (2021). I tried to get into UTSW- SW Dallas. Chanlder, R. E. et al. Occupational therapy has benefited Johns Hopkins patients for more than 100 years and continues to advance for optimal patient care. When I heard people describe what they were feeling, they sounded very much like my patients with POTS, says Tae Chung, a Johns Hopkins physiatrist with a joint appointment in the Johns Hopkins Department of Neurology and Neurosurgery, and director of the Johns Hopkins Postural Orthostatic Tachycardia Syndrome (POTS) Program. There does appear to be a small signal associating COVID-19 vaccines with POTS occurring after vaccine exposure within 90 days, Kwan told Dador. Use the Previous and Next buttons to navigate the slides or the slide controller buttons at the end to navigate through each slide. The likelihood of getting diagnosed with postural orthostatic tachycardia syndrome (POTS) increases after both COVID-19 and vaccination against SARS-CoV-2 infection, although COVID-19 itself poses a greater risk, observational data suggest. Article I took it and felt better GI wise than I had since January. Disclaimer. Please use one of the following formats to cite this article in your essay, paper or report: Toshniwal Paharia, Pooja Toshniwal Paharia. Among the post-SARS-CoV-2 vaccination cohort of 284,592 individuals, the average age was 52.0years, 57.0% were women, and 63% were Whites. Julie Wu. Am. Med. Since the introduction of COVID-19 vaccines in the USA in December 2020, vaccination against SARS-CoV-2 has remained the most effective and influential global public health strategy to mitigate the pandemic. Nous, Yahoo, faisons partie de la famille de marques Yahoo. You are using a browser version with limited support for CSS. 2017 Nov;61(5):577-582. doi: 10.1016/j.jadohealth.2017.08.004. In collaboration with the Johns Hopkins Post-Acute COVID-19 Team (PACT) service, the Johns Hopkins Division of Infectious Disease and other domestic and international partners, Chung is coordinating research to understand the incidence of POTS after COVID-19 and whether the incidence is the same as after other infections. The primary and secondary cohorts comprised COVID-19 vaccinees and SARS-CoV-2-infected individuals, respectively. We are vaccinating all eligible patients. Concerning POTS-related diagnoses, post-COVID-19 risks were 5.4-fold greater compared to the risks post-SARS-CoV-2 vaccinations. COVID-19 was associated with greater odds of both POTS-associated diagnoses (OR 1.52; 95% CI 1.33-1.72) and common primary care diagnoses (OR 1.40; 95% CI 1.31-1.50). Individuals with POTS-related diagnoses (n=1,924) post-SARS-CoV-2 vaccination had similar vaccination and demographic profiles as the vaccinated population. However, reports of post-vaccination adverse events involving various cardiovascular and neurological manifestations, including POTS, have been mounting in the Vaccine Adverse Event Reporting System1. He prescribed 20 pills 4 x daily for 5 days. I became very ill and no success in controlling the symptoms until the cardiologist at Mayo diagnosed me with POTS and instructed me on the changes I needed to make to get the symptoms to subside. The authors declare that they have no conflict of interest. Anyone you share the following link with will be able to read this content: Sorry, a shareable link is not currently available for this article. But there are various treatments for POTS that have been effective for many patients.. Please enable it to take advantage of the complete set of features! So he has offered to write me a prescription for Domperidone available out of Canada. People could self-report pre-existing conditions when getting the vaccine or making a VAERS report, but it is not required in VAERS. We hope that large prospective studies utilizing the new ICD-10 diagnostic code specific for POTS, which has been implemented by the US Center for Disease Control and Prevention committee as of October 1, 2022, can be conducted in the future. She is the highest ranking Australian medical doctor to admit to being COVID-19 vaccine injured (read more here):"This is an issue that I have witnessed first-hand with my wife who suffered a severe neurological reaction to her first Pfizer vaccine within . Most patients have trouble getting a diagnosis, which can take years, he said. Please note that medical information found This is a summary of: Kwan, A. C. et al. The main analysis was repeated with the second vaccine dose as the index study exposure and using cluster bootstrapping. If we can understand the relationship between COVID-19 and POTS, it will also help us understand the cause of POTS.. For some patients, recovery from acute SARS-CoV-2 infection may involve continuing, recurrent, or new symptoms and clinical findings that persist for weeks, months, or longer. Two sequencesymmetry analyses were performed with different retrospective cohorts of individuals who received COVID-19 vaccinations and those with COVID-19 history. Postural orthostatic tachycardia syndrome after mRNA COVID-19 vaccine. Slider with three articles shown per slide. Even without clear mechanisms to explain the findings, the medical community should be aware of the potential links between COVID-19 and vaccination and POTS, Kwan said. Bisaccia, G. et al. Sanada Y, Azuma J, Hirano Y, Hasegawa Y, Yamamoto T. Cureus. Res. The selection of a physician should be made by you after careful . Despite these limitations, the study by Kwan et al.12 is of major importance to POTS research and patient care for several reasons. If your child caught COVID-19 and went on to develop symptoms of long COVID, then you'll be all too familiar with the knock-out exhaustion that defines this globally trending, post-viral malaise. Twenty-nine (93.5%), one (3.2%), and one (3.2%) received Pfizer, Moderna, and Oxford vaccines, respectively. The study, published in Nature Cardiovascular Research on Dec. 12, analyzed data from more than 280,000 patients who received a COVID-19 vaccine and more than 12,000 patients with a confirmed . the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in permanently. CRF is committed to igniting the next wave of innovation in research and education that will help doctors save and improve the quality of their patients lives. Masks are required inside all of our care facilities, COVID-19 testing locations on Maryland.gov, Johns Hopkins Postural Orthostatic Tachycardia Syndrome (POTS) Program. In this interview, we speak to Ceri Wiggins, a Director at AstraZeneca, about the many applications of CRISPR and its role in discovering new COPD therapies. Rev. Kwan told Dador research also showed that the COVID-19 vaccine actually offers substantial protection against POTS. We set out to identify the incidence of new POTS-related diagnoses that occur after COVID-19 vaccination. 2022;Epub ahead of print. Apparent risks of postural orthostatic tachycardia syndrome diagnoses after COVID-19 vaccination and SARS-CoV-2 COVID infection. 32, 307311 (2022). In a sequence-symmetry analysis, which used individuals as their own controls and compared risks in the 90 days before exposure with those in a similar interval after exposure, the likelihood of receiving one of these diagnoses was higher after vaccination (OR 1.33; 95% CI 1.25-1.41). Never got vaccinated. Vaccination Still Best Option for Protection, Asked about potential mechanisms to explain the findings, Kwan said POTS is typically thought of as an issue with the autonomic nervous system, which maybe damaged by COVID-19. In the SARS-CoV-2 population, for most conditions studied, post-infection rates were higher than post-vaccination rates (Fig. Further research is required to investigate post-SARS-CoV-2 vaccination POTS etiology and incidence. TCTMD All rights reserved. Further, sex-stratified analyses were performed. "What is the relation between COVID-19 vaccination and new POTS-related diagnoses?". Sex stratification yielded comparable findings, with marginally and non-significantly greater myocarditis cases among males, probably because of low rates of diagnoses in outpatient settings. Med. A case of transient POTS following COVID-19 vaccine Acta Neurol Belg. Thank you! Would you like email updates of new search results? Patients with postural orthostatic tachycardia syndrome, a disorder of the autonomic nervous system, can experience a rapid heart beat, fainting and dizziness. For most of the conditions investigated, post-COVID-19 rates were greater than those observed post-SARS-CoV-2 vaccinations. By midday I did not have these symptoms. Studies examining long COVID may hopefully help researchers further . The symptoms of POTS include but are not limited to lightheadedness (occasionally with fainting), difficulty thinking and concentrating (brain fog), fatigue, intolerance of exercise, headache, blurry vision, palpitations, tremor and nausea. Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA, Dysautonomia Clinic, Williamsville, NY, USA, Department of Cardiology, Karolinska University Hospital, and Department of Medicine, Karolinska Institute, Stockholm, Sweden, You can also search for this author in Second, it clearly demonstrates that POTS and POTS-associated comorbidities occur more frequently after COVID vaccination than before, and much more frequently than myocarditis, which, despite increasing at a higher rate after vaccination, remains a rare post-vaccination complication. 2021 Apr;69(2):205-211. doi: 10.1007/s12026-021-09185-5. Methodol. Overall, the odds of post-COVID-19 new POTS-related diagnoses (1.5, n=1004) were greater than the odds for common primary care diagnoses (1.4, n=3325). Mar, P. L. & Raj, S. R. Annu Rev Med. the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in From these results, we can conclude that POTS might be occurring at a higher-than-expected frequency following COVID-19 vaccination, although at an overall rate lower than the frequency of POTS occurring following SARS-CoV-2 infection. The study cohort individuals were identified from the Cedars-Sinai health system of Los Angeles County between 2020 and 2022. Onset of Postural Orthostatic Tachycardia Syndrome (POTS) Following COVID-19 Infection: A Pediatric Case Report. (2023) Efficacy of first dose of covid-19 vaccine versus no vaccination on symptoms of patients with long covid: target trial emulation based on ComPaRe e-cohort. Apparent risks of postural orthostatic tachycardia syndrome diagnoses after COVID-19 vaccination and SARS-Cov-2 Infection, https://www.nature.com/articles/s44161-022-00177-8, Pathogenicity of SARS-CoV-2 viral components on human periodontal tissues and cells, Study results provide strong evidence for association of genetic markers to long COVID mappable to fatigue, Evidence that cross-reactive immunity from common human coronaviruses can influence response to SARS-CoV-2. Res. Owned and operated by AZoNetwork, 2000-2023. A similar analysis was performed in over 12,000 SARS-CoV-2 infection records. Third, the generalizability of this report is limited to a specific population. (2022, December 14). . There is no way to tease that information out of the VAERS data. 'Given that COVID-19 vaccination elicits an immunological response to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein, there is biological plausibility for a similar, even if attenuated, systemic response to vaccine when compared to that seen from viral exposure.'Researchers 'evaluated the relation between COVID-19 vaccination and new POTS-related diagnoses . Therefore, deriving precise estimates of risk per exposure is difficult, and follow-up studies are needed to determine the absolute risk of POTS after vaccination. Annu Rev Med. Lorsque vous utilisez nos sites et applications, nous utilisons des, authentifier les utilisateurs, appliquer des mesures de scurit, empcher les spams et les abus; et. Get the most important science stories of the day, free in your inbox. July I visited my cardiologist, she ran Nuclear Stress test, normal, I wore a 24 hr heart monitor and my heart rate was as high as 165 at one point! Norovirus, the No. The investigators found that the risk of developing POTS after vaccination is less than five cases per million doses. Whatever side of the covid/vaccine side you are on people actually died . These study results are not intended to discourage use of the COVID-19 vaccine, especially given the relatively higher risk of developing POTS after SARS-CoV-2 infection. Neurol Sci. Hi Sue, to be clear, I am not worried about developing POTS as a reaction to either the vaccine or COVID; I already have it. I hope this helps you with your decision-making. 1997;20:15611568. I suggest that any of us with these issues consider sticking with Pfizer. Impact of COVID-19 Vaccination on Heart Rate Variability: A Systematic Review. Kwon, A. et al. Unable to load your collection due to an error, Unable to load your delegates due to an error, Quantitative sudomotor axon reflex test revealed normal response in the forearm (. National Library of Medicine 18, 115 (2018). Among the COVID-19 vaccinees, the odds of novel POTS, myocarditis, and dysautonomia diagnoses were greater, albeit with low occurrence rates. SARS-CoV-2 vaccinations elicit immune responses to the SARS-CoV-2 S (spike) glycoprotein. The last point is particularly poignant and clinically relevant, as it provides compelling evidence that can be referenced during physicianpatient encounters in support of vaccination and against vaccine hesitancy. We hope that our results feed back to the community in a positive way and spur further research to solve the issues presented to the medical community as a whole by the COVID-19 pandemic. Comparing a 90-day period before exposure and a 90-day period after exposure, in fact, the probability of receiving a POTS-associated diagnosis was more than fivefold higher after a bout of COVID-19 than after vaccination (OR 5.35; 95% CI 5.05-5.68), according to researchers led by Alan Kwan, MD (Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA). We are able to more definitively say that we think that this is a real observation, he said. It's not clear yet whether patients are developing POTS after COVID-19 for some reason above and beyond why any other infections trigger POTS, or whether it's just that we're seeing a lot. A life-changing condition called POTS, which can cause fainting, irregular heartbeats and dizziness, particularly among young women, appears to be on the rise as a result of the coronavirus pandemic. An official website of the United States government. 2023 Cedars-Sinai. Thus, we examined the extent to which new diagnoses of POTS are increased following COVID-19 vaccination in our health system, a large quaternary care system in Los Angeles. Sheldon, R. S. et al. eCollection 2022 Nov. See this image and copyright information in PMC. The authors declare no competing interests. As such, some of the affected individuals may have recovered later. The primary outcomes were the diagnosis-specific odds of a new diagnosis occurring post-exposure vs. pre-exposure and the odds of acquiring a post-exposure new POTS diagnosis vs. a new CPC diagnosis. In 17 of the cases, a COVID-19 vaccine caused myocarditis, a form of heart inflammation, pericarditis, a related condition, or both. (no I dont). He put me on 50 mg 2 times per day of Metoprolol and .1mg of fludrocortisone. We avoided Moderna which has 100mcg of mRNA for shots 1 and 2, while Pizer had 30. Second, the general awareness and diagnostic vigilance of POTS and access to adequate diagnostic modalities are decisive for POTS incidence reliability. Article CV Risk Factors or Preexisting CVD: Whats Worse for COVID-19? Accordingly, patients studied received clinical care that was reviewed to be consistent with guidelines recommendations, and referral to local experts in managing POTS was often pursued in cases that warranted consideration for more specialized evaluation and therapies., Todd Neale is the Associate News Editorfor TCTMD and a Senior Medical Journalist. Chen, G. et al. Hello I have ulcerative colitis, fibromyalgia, degenerative disc disease, Reynaud'sI got the first Pfizer dose in late February and I had a very high fever by the next morning and began experience my first POTs symptoms immediately thereafter. This case report is clinically relevant to better understand the pathophysio PMC Google Scholar. I did have stones. Apparent risks of postural orthostatic tachycardia syndrome diagnoses after COVID-19 vaccination and SARS-Cov-2 Infection, Inappropriate sinus tachycardia in post-COVID-19 syndrome, Reports of acute adverse events in mRNA COVID-19 vaccine recipients after the first and second doses in Japan, COVID-19 pandemic and hypertension: an updated report from the Japanese Society of Hypertension project team on COVID-19, Long COVID: major findings, mechanisms and recommendations, Cardiac involvement in the long-term implications of COVID-19, Understanding the role of nACE2 in neurogenic hypertension among COVID-19 patients, Heart rate variability comparison between young males after 46weeks from the end of SARS-CoV-2 infection and controls, Seroconversion dynamic and SARS-CoV-2 seropositivity in unvaccinated population during the first and second outbreaks in Mexico, https://doi.org/10.1038/s44161-022-00177-8. J. Neurol. On my third ER visit for another severe POTS episode, the ER doctor did give me a prescription for Metoclopramide(GI drug..among other things). My daughter and I both have autoimmune conditions: I have lupus. March 2022 Gallbladder removed, heart rate increasing, still have GI issues. Epub 2022 Jul 26. In a recent study published in Nature Cardiovascular Research, researchers assessed the association between POTS (postural orthostatic tachycardia syndrome) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections and coronavirus disease 2019 (COVID-19) vaccinations. A lot of people with chronic fatigue and heart palpitations end up in physiatry clinics because they are debilitated. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). 17, e52 (2010). Res. Continued studies is the the only way to get down to the truth and find treatments that work. I had my second dose as appropriate in late March. COVID-19 Dysautonomia. doi: 10.1002/(sici)1097-4598(199712)20:12<1561::aid-mus11>, Mar PL, Raj SR. Postural orthostatic tachycardia syndrome: mechanisms and new therapies. Accuracy depends on how thorough people reporting a reaction were in reporting their history and current medical conditions, but here is what I found: Kwan, the first and corresponding author of the study, told ABC 7 news reporter Denise Dador that in reviewing patient health records, he and his team found that a small percentage of patients who received the COVID-19 vaccine experienced POTS.